| SHORT COMMUNICATION |
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| Year : 2020 | Volume
: 22
| Issue : 1 | Page : 59-61 |
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Inconclusive SARS-COV-2 reverse transcription-polymerase chain reaction test reports: Interpretation, clinical and infection control implications
Sanjay Bhattacharya, Anju Vidyadharan, Vinitha Mary Joy
Department of Microbiology, Tata Medical Center, Kolkata, West Bengal, India
Correspondence Address:
Dr. Sanjay Bhattacharya
Consultant in Microbiology, Department of Microbiology, Tata Medical Center, Kolkata, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jacm.jacm_16_20
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Inconclusive SARS CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) reports for the detection of infection in symptomatic patients or during screening of asymptomatic contacts can cause clinical, diagnostic and infection control uncertainty. It has been noted that up to 5% of COVID RT-PCR reports may be inconclusive. The reasons for these inconclusive reports are varied and may be classified into virological causes, sample collection and sample quality-related issues and finally technical issues related primarily due to problems in RNA extraction. The objective of this article is to discuss these causes and suggest corrective measures.
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